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KMID : 0861120030070020075
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Korean Journal of Oriental Preventive Medicine
2003 Volume.7 No. 2 p.75 ~ p.83
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Experimental Study on the Effects of Carthami Flos on the Hyperlipidemic Rats Induced by Triton WR-1339
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Kim Tae-Hyung
Soh Kyung-Soon
Jeong Chan-Gil
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Abstract
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In order to study the effects of Carthami Flos on the hyperlipidemia, we made hyperlipidemic model by injection of Triton WR-1339 150mg/kg to rats during 3 days. 1 hour after the final injection of Triton WR-1339, Carthami Flos extracts were administered to rats 2ml/200g(p.o.). And after 24 hours, we measured the levels of serum total cholesterol, triglyceride, phospholipid and HDL-cholesterol. The results are summarized as follows. 1) Serum total cholesterol levlel of Sample group was significantly decreased compared with Control group(p<0.05). 2) Serum triglyceride level of Sample group was significantly decreased compared with Control group(p<0.01) 3) Serum phospholipid levlel of Sample group was significantly decreased compared with Control group(p<0.05). 4) Serum HDL-cholesterol level of Sample group was significantly increased compared with Control group(p<0.05).
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KEYWORD
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Carthami Flos, Triton WR-1339, hyperlipidemic rats, total cholesterol, triglyceride, phospholipid, HDL-cholesterol
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